Winning Technology: Missouri Osteochondral Preservative MOPS
MTF Biologics in conjunction with Missouri Orthopedic Institute & ConMed
Inventors: James L. Cook, DVM, PhD, OTSC, Aaron M. Stoker, M.S., Ph.D., Clark T. Hung, PhD., Eric Lima, Ph.D.
Engineers: Clark T. Hung, Ph.D., Eric Lima, Ph.D.
Longer chondrocyte viability in an osteochondral implants from MTF Foundation—the most trusted allograft supplier—was a no-brainer for this year’s best technology in sports medicine award.
Named “The Missouri Osteochondral Preservation System (MOPSSM)” because of the close partnership with the University of Missouri, this innovative allograft was designed by MTF’s engineers to more completely preserve donated cartilage, bone, meniscus, ligament and intervertebral disc during the required disease testing period and the storage period before transplantation, which is typically up to 70 days from procurement.
This novel method, which complies with FDA Regulation 21 CFR Part 1271, Human Cells, Tissues, Cellular and Tissue Based Products (HCT/Ps), offers many more benefits than current preservation systems including the use of closed containers, serum-free media that includes dexamethasone, and the ability to be stored at room temperature.
This system extends chondrocyte viability which usually falls below essential levels within 28 days after procurement with current tissue bank preservation protocols. The Missouri Osteochondral Preservation System (MOPS) has been validated to maintain essential chondrocyte viability, articular cartilage extracellular matrix composition, and material properties in all grafts for at least 56 days after procurement. It is not regulated as a medical device.
Fresh osteochondral allografts are in limited supply. Longer preservation times with the Missouri Osteochondral Preservation System means more allografts will be available when needed. These allografts have also been associated with lower total complication rates (p = .044) compared to standard-of-care grafts.
Winning Technology: Pivot Guardian Distractor System
Stryker Corp.
Inventor: Dr. Omer Mei-Dan
Engineers: William Kaiser, Mary O’Grady, Conrad Smith, Jeremy Graul, Edison Lopes, Joe Layton, Miguel Figuroa Diaz.
The first-ever post-free hip distraction system. That is the Pivot Guardian Distraction System, a Class I device.
Complications around the perineal post and current boot technology in hip arthroscopy include nerve dysfunction symptoms and problems in the groin area have long bedeviled sports medicine physicians.
Dipmann et al. published in Arthroscopy in 2014 found 46% of hip arthroscopy patients reported nerve dysfunction symptoms. In addition, 22% still reported symptoms after 26 weeks and 18% still reported symptoms after one year. And Frandsen et al. published in the Journal of Hip Preservation Surgery in 2017 found 32% of patients reported problems in groin area.
The problems were temporary and disappeared typically within two to four weeks. Some patients reported numbness after two months.
Now Stryker has developed a very novel system which reduces groin complications, minimizes heel slip, and improves range of motion for hip arthroscopy.
It also gives surgeons better visibility, allowing them to see and do more which also improves patient outcomes.
A recent study of 1,000 hip arthroscopies performed without the use of a perineal post found in every case that the procedure allows safe, adequate, reproducible access to the hip joint without groin-related soft tissue or nerve complications. The study was published in March of 2018 in The American Journal of Sports Medicine. Patent filings occurred between 2015 and 2018.
