Two Hormones Slow OA – Amazing Mouse Study

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Kind of a big deal. Apparently, in years past, somebody forgot to specify gender when they were ordering mice for osteoarthritis (OA) lab studies.

Why does that matter? Quoting, literally, from the title of this new study from researchers at Spaulding Rehabilitation, a member of the Mass General Brigham Health System: “Menopause-induced 17β-estradiol and progesterone loss increases senescence markers, matrix disassembly and degeneration in mouse cartilage.”